Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization.

PLoS biology - 1 Jan 2004

Huh Jun R, Vernooy Stephanie Y, Yu Hong, Yan Nieng, Shi Yigong, Guo Ming, Hay Bruce A

Abstract excerpt

Spermatozoa are generated and mature within a germline syncytium. Differentiation of haploid syncytial spermatids into single motile sperm requires the encapsulation of each spermatid by an independent plasma membrane and the elimination of most sperm cytoplasm, a process known as individualizati...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptotic Protease-Activating Factor 1
Share to Caspases
Share to Cell Death

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatty Acid Desaturases

Share to Inhibitor of Apoptosis Proteins

Share to Spermatids

Share to Spermatozoa

Share to Testis

Source

Open in PubMed Open full text

Identifiers

PMID: 14737191
DOI: 10.1371/journal.pbio.0020015
PMCID: PMC300883

Genes

FADD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14737191-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization.PMID 14737191Read ↗

The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process.Semantic proximity Read ↗

A novel F-box protein is required for caspase activation during cellular remodeling inDrosophilaSemantic proximity Read ↗

Gradients of a ubiquitin E3 ligase inhibitor and a caspase inhibitor determine differentiation or death in spermatids.Semantic proximity Read ↗

The Drosophila caspase DRONC is regulated by DIAP1.Semantic proximity Read ↗

Control of apoptosis by Drosophila DCAF12.Semantic proximity Read ↗

A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila.Semantic proximity Read ↗

Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.Semantic proximity Read ↗

drICE is an essential caspase required for apoptotic activity in Drosophila cellsSemantic proximity Read ↗

Cleavage of the apoptosis inhibitor DIAP1 by the apical caspase DRONC in both normal and apoptotic Drosophila cells.Semantic proximity Read ↗

Drosophila spermiogenesisSemantic proximity Read ↗

The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in Drosophila.Semantic proximity Read ↗

Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.