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Article

Association of thromboxane A2 receptor gene polymorphisms with cerebral infarction in a Chinese population.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Oct 2013

Zhao Jing, Zheng Lan, Fei Qingzhou, Fu Yi, Weng Yingfeng, Wu Hui, Li Huanyin, Jun Qi, Shao Jingshan, Xu Yuming

Abstract excerpt

Platelet aggregation is crucial for the development of cerebral infarction (CI) and it is markedly increased due to the binding of thromboxane A2 (TXA2) to its receptor (TXA2R). Therefore, TXA2R plays a central role in the pathogenesis of atherosclerosis and thrombosis. This study aimed to investigate the relationship between human TXA2R gene single nucleotide polymorphisms (SNPs) and non-cardiogenic CI in a...

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PMID: 23456445
DOI: 10.1007/s10072-013-1340-x

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