Article
Mannan-binding lectin-2 (MBL2) gene polymorphisms in prenatal and perinatal cytomegalovirus infections.
Molecular immunology - 1 Sept 2011
Szala Agnieszka, Paradowska Edyta, Nowakowska Dorota, Swierzko Anna S, Dzierzanowska-Fangrat Katarzyna, Sokolowska Anna, Studzinska Miroslawa, Gaj Zuzanna, Suski Patrycja, Kasztelewicz Beata, Wilczynski Jan, Cedzynski Maciej
Abstract excerpt
Cytomegalovirus (CMV) is the leading cause of congenital infections among neonates. About 10% of newborns with such an infection have clinical symptoms at birth and about 1% of infected fetuses die due to developmental malformations. Mannan-binding lectin (MBL) is considered to be an important factor in innate immunity. Its deficiency is believed to predispose to various (including viral) infections. The aim of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
