Article
Programming of human umbilical cord mesenchymal stem cells in vitro to promote pancreatic gene expression.
Molecular medicine reports - 1 Sept 2013
Wang Hongwu, Yang Yuping, Ho Guyu, Lin Xiaobo, Wu Weizhao, Li Weizhong, Lin Limin, Feng Xueyong, Huo Xia, Jiang Jikai, Liu Xiaoshan, Huang Tianhua, Wei Chiju, Ma Lian
Abstract excerpt
Human umbilical cord mesenchymal stem cells (HUMSCs) are candidates for tissue engineering and may potentially be used for transdifferentiation into pancreatic endocrine cells. The adenoviral vector is effective in transducing genes into stem cells that are refractory to gene delivery by non‑viral approaches. qPCR was used to detect the pancreatic endogenous gene expression of HUMSCs transfected by islet...
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