Article
Prognostic implication of the CpG island methylator phenotype in colorectal cancers depends on tumour location.
British journal of cancer - 20 Aug 2013
Bae J M, Kim J H, Cho N-Y, Kim T-Y, Kang G H
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) is usually categorised as proximal or distal CRC. Recently, many researchers have tried to determine the molecular heterogeneity of CRCs along bowel subsites. However, the differential effects of the CpG island methylator phenotype (CIMP) and microsatellite instability (MSI) on the clinical outcome according to tumour location are not well-known. METHODS: We analysed...
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