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Article

Full-length PGC-1α salvages the phenotype of a mouse model of human neuropathy through mitochondrial proliferation.

Human molecular genetics - 20 Dec 2013

Rona-Voros Krisztina, Eschbach Judith, Vernay Aurélia, Wiesner Diana, Schwalenstocker Birgit, Geniquet Pauline, Mousson De Camaret Bénédicte, Echaniz-Laguna Andoni, Loeffler Jean-Philippe, Ludolph Albert C, Weydt Patrick, Dupuis Luc

Abstract excerpt

Increased mitochondrial mass, commonly termed mitochondrial proliferation, is frequently observed in many human diseases directly or indirectly involving mitochondrial dysfunction. Mitochondrial proliferation is thought to counterbalance a compromised energy metabolism, yet it might also be detri...

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Source

Identifiers

PMID: 23900073
DOI: 10.1093/hmg/ddt359

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23900073-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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