Article
Body Mass Index and Polycystic Ovary Syndrome: A 2-Sample Bidirectional Mendelian Randomization Study.
The Journal of clinical endocrinology and metabolism - 1 Jun 2020
Zhao Yalin, Xu Yuping, Wang Xiaomeng, Xu Lin, Chen Jianhua, Gao Chengwen, Wu Chuanhong, Pan Dun, Zhang Qian, Zhou Juan, Chen Ruirui, Wang Zhuo, Zhao Han, You Li, Cao Yunxia, Li Zhiqiang, Shi Yongyong
Abstract excerpt
BACKGROUND: Observational studies have shown a link between elevated body mass index (BMI) and the risk of polycystic ovary syndrome (PCOS). While Mendelian randomization (MR) studies in Europeans have suggested a causal role of increased BMI in PCOS, whether the same role is suggested in Asians has yet to be investigated. We used MR studies to infer causal effects using genetic data from East Asian populations....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.