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Article

Causal Association Between BMI and Polycystic Ovarian Syndrome: Bidirectional 2-Sample Mendelian Randomization Study.

The Journal of clinical endocrinology and metabolism - 18 Dec 2024

Fang Yifan, Liu Lan, Yang Yingying, Zhang Bing, Xie Siqi

Abstract excerpt

OBJECTIVE: This study aimed to explore the causal effect of body mass index (BMI) on polycystic ovarian syndrome (PCOS). METHODS: Genome-wide association data for BMI and PCOS were sourced from the Mendelian randomization (MR) base platform. Significantly associated single nucleotide polymorphisms (SNPs) for BMI served as instrumental variables in bidirectional 2-sample MR analyses to investigate the causal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38943662
DOI: 10.1210/clinem/dgae446

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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