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Article

A clinical model for identifying radiosensitive tumor genotypes in non-small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2013

Johung Kimberly L, Yao Xiaopan, Li Fangyong, Yu James B, Gettinger Scott N, Goldberg Sarah, Decker Roy H, Hess Judith A, Chiang Veronica L, Contessa Joseph N

Abstract excerpt

PURPOSE: Non-small cell lung cancer (NSCLC) includes a spectrum of radiosensitive and radioresistant tumors. However, little is known about the molecular determinants of cellular radiation responses. We examined clinical outcomes after gamma knife radiotherapy for NSCLC intracranial metastases to evaluate the use of this model for determining radiosensitive tumor genotypes. EXPERIMENTAL DESIGN: Between 2005 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23897899
DOI: 10.1158/1078-0432.CCR-13-0836

Genes

ALK
EGFR
EML4
KRAS
EGF

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