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Impact of EGFR Mutation Subtypes and TKI Generations on Clinical Outcomes in Lung Adenocarcinoma Patients with Brain Metastases Treated with Gamma Knife Radiosurgery

2025-03-25

Abstract excerpt

<title>Abstract</title> <p>Background Brain metastases are a common and severe complication in patients with lung adenocarcinoma (ADC) harboring epidermal growth factor receptor (EGFR) mutations. Gamma Knife Radiosurgery (GKRS) is a standard treatment for brain metastases, and its efficacy may be influenced by the type of EGFR mutation and the generation of tyrosine kinase inhibitors (TKIs) used. This retrospecti...

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Literature Corpus work
17c19682-c198-5ff2-be1e-0907dbf94ca4
DOI
10.21203/rs.3.rs-6272825/v1
Open publication

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