Article
Epidermal growth factor receptor mutation predicts favorable outcomes in non-small cell lung cancer patients with brain metastases treated with stereotactic radiosurgery.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Feb 2018
Yang Wen-Chi, Xiao Furen, Shih Jin-Yuan, Ho Chao-Chi, Chen Ya-Fang, Tseng Ham-Min, Chen Kuan-Yu, Liao Wei-Yu, Yu Chong-Jen, Yang James Chih-Hsin, Kuo Sung-Hsin, Cheng Jason Chia-Hsien, Yang Pan-Chyr, Hsu Feng-Ming
Abstract excerpt
PURPOSE: The impact of epidermal growth factor receptor (EGFR) mutations on radiotherapy for brain metastases (BM) is undetermined. We evaluated the effects of EGFR mutation status on responses and outcomes in non-small cell lung cancer (NSCLC) patients with BM, treated with upfront or salvage stereotactic radiosurgery (SRS). METHODS AND MATERIALS: From 2008 to 2015, 147 eligible NSCLC patients with 300 lesions...
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