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Directed Differentiation of Human Embryonic Stem Cells into the Pancreatic Endocrine Lineage

1 Aug 2007

Abstract excerpt

Human embryonic stem (hES) cells represent a potentially unlimited source of transplantable beta-cells for the treatment of diabetes. Here we describe a differentiation strategy that reproducibly directs HES3, an National Institutes of Health (NIH)-registered hES cell line, into cells of the pancreatic endocrine lineage. HES3 cells are removed from their feeder layer and cultured as embryoid bodies in a...

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PMID: 17784830
DOI: 10.1089/scd.2007.0029

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