Article
Germline single nucleotide polymorphisms associated with response of urothelial carcinoma to platinum-based therapy: the role of the host.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Sept 2013
Gallagher D J, Vijai J, Hamilton R J, Ostrovnaya I, Iyer G, Garcia-Grossman I R, Kim P H, Przybylo J A, Alanee S, Riches J C, Regazzi A M, Milowsky M I, Offit K, Bajorin D F
Abstract excerpt
BACKGROUND: Variations in urothelial carcinoma (UC) response to platinum chemotherapy are common and frequently attributed to genetic and epigenetic variations of somatic DNA. We hypothesized that variations in germline DNA may contribute to UC chemosensitivity. PATIENTS AND METHODS: DNA from 210...
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