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Article

The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice.

PloS one - 16 Nov 2010

Gao Xue, Shin Yong-Hyun, Li Min, Wang Fei, Tong Qiang, Zhang Pumin

Abstract excerpt

FTO (fat mass and obesity associated) was identified as an obesity-susceptibility gene by several independent large-scale genome association studies. A cluster of SNPs (single nucleotide polymorphism) located in the first intron of FTO was found to be significantly associated with obesity-related traits, such as body mass index, hip circumference, and body weight. FTO encodes a protein with a novel C-terminal...

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Source

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Identifiers

PMID: 21103374
DOI: 10.1371/journal.pone.0014005
PMCID: PMC2982835

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice.PMID 21103374Read ↗

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FTO and obesity: mechanisms of association.Semantic proximity Read ↗

Programming effects of FTO in the development of obesity.Semantic proximity Read ↗

Role of FTO in Adipocyte Development and Function: Recent InsightsSemantic proximity Read ↗

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