Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases

1 Dec 2015

Abstract excerpt

Single-nucleotide polymorphisms within intron 1 of the FTO (fat mass and obesity-associated) gene are associated with enhanced FTO expression, increased body weight, obesity and type 2 diabetes mellitus (T2DM). The N (6) -methyladenosine (m(6)A) demethylase FTO plays a pivotal regulatory role for postnatal growth and energy expenditure. The purpose of this review is to provide translational evidence that links...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital Anomalies and Fetal Surgery
Share to Epigenetics and DNA Methylation
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26691922
DOI: 10.1186/s12967-015-0746-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseasesPMID 26691922Read ↗

Milk’s Role as an Epigenetic Regulator in Health and DiseaseSemantic proximity Read ↗

Risk of Fat Mass- and Obesity-Associated Gene-Dependent Obesogenic Programming by Formula Feeding Compared to BreastfeedingSemantic proximity Read ↗

FTO as an epigenetic regulator in metabolic and inflammatory diseasesSemantic proximity Read ↗

The biology of FTO: from nucleic acid demethylase to amino acid sensor.Semantic proximity Read ↗

The Pathogenic Role of Persistent Milk Signaling in mTORC1- and Milk- MicroRNA-Driven Type 2 Diabetes MellitusSemantic proximity Read ↗

Milk exosomal miRNAs: potential drivers of AMPK-to-mTORC1 switching in β-cell de-differentiation of type 2 diabetes mellitusSemantic proximity Read ↗

Weighted Epigenetic Profiling of Milk miRNAs Across Human, Bovine, and Camel Species: A Comparative Global ScoreSemantic proximity Read ↗

Milk disrupts p53 and DNMT1, the guardians of the genome: implications for acne vulgaris and prostate cancerSemantic proximity Read ↗

Human milk extracellular vesicle miRNA expression and associations with maternal characteristics in a population-based cohort from the Faroe IslandsSemantic proximity Read ↗

Immunomodulatory Properties of Human Breast Milk: MicroRNA Contents and Potential Epigenetic EffectsSemantic proximity Read ↗

Exosomes of pasteurized milk: potential pathogens of Western diseasesSemantic proximity Read ↗

Milk Exosomal microRNAs: Postnatal Promoters of β Cell Proliferation but Potential Inducers of β Cell De-Differentiation in Adult LifeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.