Article
[Desmoplakin expression silencing affects cardiac voltage-gated sodium channel Nav1.5 in HL-1 cells].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Jul 2013
Zhang Qianhuan, Deng Chunyu, Rao Fang, Liu Xiaoying, Mai Liping, Zhu Jiening, Tan Honghong, Wu Shulin
Abstract excerpt
OBJECTIVE: To investigate the association of desmoplakin with the distribution and function of Nav1.5 by RNA silencing technology in HL-1 cells. METHODS: HL-1 cells with desmoplakin expression suppression by RNA silencing were examined for desmoplakin and Nav1.5 protein expressions by Western blotting, and the distribution and co-location of desmoplakin and Nav1.5 protein were detected by immunofluorescence...
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