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Mutational analysis of single-stranded DNA templates active in the in vitro initiation assay for adenovirus DNA replication.

Virology - 1 Sept 1990

Dobbs L, Zhao L J, Sripad G, Padmanabhan R

Abstract excerpt

Three distinct domains, A, the minimal origin, as well as B and C, the binding sites for the host nuclear factors, are required for efficient initiation of adenovirus (Ad) DNA replication at the termini. The initiation reaction was examined using partially purified nuclear extracts and various single-stranded oligomers as DNA templates. We observed that single-stranded oligomers containing Ad2 minimal origin...

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PMID: 2389559
DOI: 10.1016/0042-6822(90)90377-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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