Article
Paraoxonase (PON1) 55 polymorphism and association with systemic lupus erythematosus.
Iranian journal of allergy, asthma, and immunology - 9 Jul 2013
Bahrehmand Fariborz, Vaisi-Raygani Asad, Ahmadi Reza, Kiani Amir, Rahimi Zohreh, Tavilani Heidar, Pourmotabbed Tayebeh
Abstract excerpt
Paraoxonase-1 (PON1) is a serum HDL-bound enzyme that hydrolyzes a number of aromatic carboxylic acid esters including lipid peroxides, preventing LDL oxidation. Systemic lupus erythematosus (SLE) patients are at greater risk of oxidative stress, which is associated with abnormal plasma lipid metabolism. In this study, association of PON-55 polymorphism with serum arylesterase (ARE) activities, malondialdehyde...
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