Article
Paraoxonase 1 (PON1) 55 polymorphism, lipid profiles and psoriasis.
The British journal of dermatology - 1 Dec 2012
Asefi M, Vaisi-Raygani A, Bahrehmand F, Kiani A, Rahimi Z, Nomani H, Ebrahimi A, Tavilani H, Pourmotabbed T
Abstract excerpt
BACKGROUND: Paraoxonase 1 (PON1) is a serum high-density lipoprotein-bound enzyme with antioxidant function. It hydrolyses lipid peroxides, protecting low-density lipoproteins from oxidative modifications. Patients with psoriasis are at greater risk of oxidative stress, which is associated with abnormal plasma lipid metabolism. OBJECTIVES: In this study, association of the PON1 55 M allele with serum arylesterase...
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