Article
Regulated membrane protein entry into flagella is facilitated by cytoplasmic microtubules and does not require IFT.
Current biology : CB - 5 Aug 2013
Belzile Olivier, Hernandez-Lara Carmen I, Wang Qian, Snell William J
Abstract excerpt
The membrane protein composition of the primary cilium, a key sensory organelle, is dynamically regulated during cilium-generated signaling [1, 2]. During ciliogenesis, ciliary membrane proteins, along with structural and signaling proteins, are carried through the multicomponent, intensely studied ciliary diffusion barrier at the base of the organelle [3-8] by intraflagellar transport (IFT) [9-18]. A favored...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
