Article
Intraflagellar transport particles participate directly in cilium-generated signaling in Chlamydomonas.
Cell - 5 May 2006
Wang Qian, Pan Junmin, Snell William J
Abstract excerpt
Primary cilia are widely used for signal transduction during development and in homeostasis and are assembled and maintained by intraflagellar transport (IFT). Here, we have dissected the role of IFT in signaling within the flagella (structural and functional counterparts of cilia) of the biflagellated green alga Chlamydomonas. Using a conditional IFT mutant enables us to deplete the IFT machinery from intact,...
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