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Article

Gluthatione-S-transferase T1-null genotype predisposes adults to acute promyelocytic leukemia; a case-control study.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Mandegary Ali, Rostami Shahrbanou, Alimoghaddam Kamran, Ghavamzadeh Ardeshir, Ghahremani Mohammad Hossein

Abstract excerpt

Polymorphisms of glutathione S-transferase (GST) proteins are correlated with elevated risk of many cancers including hematologic malignancies. Particularly concerning acute promyelocytic leukemia (APL), the studies on association between GSTM1, GSTT1 and GSTP1 and the disease predisposition are scarce and contradictory. The aim of this study was to examine whether polymorphic variations in GST confer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21875282

Genes

GSTT1
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Research trail→

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Gluthatione-S-transferase T1-null genotype predisposes adults to acute promyelocytic leukemia; a case-control study.PMID 21875282Read ↗

Risk effects of GST gene polymorphisms in patients with acute myeloid leukemia: a prospective study.Semantic proximity Read ↗

Deletion of GSTM1 and T1 genes as a risk factor for development of acute leukemia.Semantic proximity Read ↗

Glutathione S-transferase gene polymorphisms and susceptibility to acute myeloid leukemia: meta-analyses.Semantic proximity Read ↗

Meta-analysis study of glutathione-S-transferases (GSTM1, GSTP1, and GSTT1) gene polymorphisms and risk of acute myeloid leukemia.Semantic proximity Read ↗

Increased risk for acute myeloid leukaemia in individuals with glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) gene defects.Semantic proximity Read ↗

Glutathione S-transferase polymorphisms in children with myeloid leukemia: a Children's Cancer Group study.Semantic proximity Read ↗

Polymorphic variation within the glutathione S-transferase genes and risk of adult acute leukaemia.Semantic proximity Read ↗

Glutathione s-transferase polymorphisms (GSTM1, GSTP1 and GSTT1) and the risk of acute leukaemia: a systematic review and meta-analysis.Semantic proximity Read ↗

Genetic polymorphisms analysis of glutathione S-transferase M1 and T1 in children with acute lymphoblastic leukemia.Semantic proximity Read ↗

Association of GSTM1 and GSTT1 deletion polymorphisms with Pakistani aplastic anemia patients and controls and meta-analysis.Semantic proximity Read ↗

Increased prevalence of GSTM(1) null genotype in patients with myelodysplastic syndrome: a case-control study.Semantic proximity Read ↗

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