Article

Multi-species atlas resolves an axolotl limb development and regeneration paradox

2023-03-01

Abstract excerpt

Humans and other tetrapods are considered to require apical-ectodermal-ridge, AER, cells for limb development, and AER-like cells are suggested to be re-formed to initiate limb regeneration. Paradoxically, the presence of AER in the axolotl, the primary regeneration model organism, remains controversial. Here, by leveraging a single-cell transcriptomics-based multi-species atlas, composed of axolotl, human, mouse,...

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Literature Corpus work: 43a6e0ca-c26a-5f51-ac1f-820f2651d8fe
DOI: 10.1101/2023.03.01.530572

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