Article
Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants.
The Journal of biological chemistry - 25 Aug 1990
Rushmore T H, Pickett C B
Abstract excerpt
We have identified previously a xenobiotic-responsive element, which we termed the beta-naphthoflavone-responsive element, between nucleotide -722 and -682 in the 5'-flanking region of the rat glutathione S-transferase Ya subunit gene (Rushmore, T.H., King, R.G., Paulson, K.E., and Pickett, C.B. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 3826-3830). The beta-naphthoflavone-responsive element is responsible for part...
Topics
- Animals
- Antioxidants
- Base Sequence
- Benzoflavones
- Cell Line
- Chloramphenicol O-Acetyltransferase
- Chromosome Deletion
- Flavonoids
- Gene Expression Regulation, Enzymologic
- Genes, Regulator