Dissecting tBHQ induced ARE-driven gene expression through long and short oligonucleotide arrays.

doi:10.1152/physiolgenomics.00214.2004

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Article

Dissecting tBHQ induced ARE-driven gene expression through long and short oligonucleotide arrays.

Physiological genomics - 21 Mar 2005

Li Jiang, Spletter Maria L, Johnson Jeffrey A

Abstract excerpt

This paper compares the gene expression profiles identified by short (Affymetrix U95AV2) or long (Agilent Hu1A) oligonucleotide arrays on a model for upregulation of a cluster of antioxidant responsive element-driven genes by treatment with tert-butylhydroquinone. MAS 5.0, dCHIP, and RMA were applied to normalize the Affymetrix data, and Lowess regression was considered for Agilent data. SAM was used to identify...

Topics

Alternative Splicing
Animals
Antioxidants
Base Pair Mismatch
Biomarkers
Cluster Analysis
DNA Repair
Databases, Genetic
Gene Expression
Gene Expression Profiling
Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Techniques

Humans

Hydroquinones

Luciferases

Mice

Mutation

Nucleic Acid Hybridization

Source

Open in PubMed

Identifiers

PMID: 15613614
DOI: 10.1152/physiolgenomics.00214.2004

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