Article
The role of Ah receptor in induction of human UDP-glucuronosyltransferase 1A1.
Methods in enzymology - 1 Jan 2005
Yueh Mei-Fei, Bonzo Jessica A, Tukey Robert H
Abstract excerpt
UDP-glucuronosyltransferases (UGTs) catalyze a major metabolic pathway initiating the transfer of glucuronic acid from uridine 5'-diphosphoglucuronic acid to endogenous and exogenous substances. Endogenous substances include bile acids, steroids, phenolic neurotransmitters, and bilirubin. Xenobiotic substances include dietary substances, therapeutics, and environmental compounds. The versatility in the selection...
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