Article
New antifungal antibiotics, pradimicins D and E. Glycine analogs of pradimicins A and C.
The Journal of antibiotics - 1 Jul 1990
Sawada Y, Nishio M, Yamamoto H, Hatori M, Miyaki T, Konishi M, Oki T
Abstract excerpt
New antifungal antibiotics pradimicins D and E were isolated from the culture filtrates of Actinomadura hibisca P157-2 (ATCC 53557) and its mutant A2660 (ATCC 53762). The structure of pradimicin D is N-[[(5S,6S)-5-O-[4,6-dideoxy-4-(methylamino)-3-O-(beta-D- xylopyranosyl)-beta-D-galactopyranosyl]...
Topics
- Actinomycetales
- Animals
- Anthracyclines
- Antibiotics, Antineoplastic
- Antifungal Agents
- Candidiasis
- Fermentation
- Fungi
- Magnetic Resonance Spectroscopy
- Male
- Mass Spectrometry
- Mice
- Mice, Inbred ICR
- Molecular Structure
- Mutation
- Spectrophotometry, Ultraviolet
- Yeasts
