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Article

Leporizines A-C: epithiodiketopiperazines isolated from an Aspergillus species.

Journal of natural products - 27 Sept 2013

Reategui Ricardo, Rhea Joshua, Adolphson Janet, Waikins Kathryn, Newell Ryan, Rabenstein John, Mocek Ulla, Luche Michele, Carr Grant

Abstract excerpt

Three new compounds named leporizines A-C have been isolated from an Aspergillus sp. strain. Their structures were elucidated by analysis of 1D and 2D NMR spectra. Leporizines A and B were isolated during dereplication of hits from a high-throughput screening campaign for correctors of the cystic fibrosis transmembrane conductance regulator (CFTR), and leporizine C was isolated while preparing additional material...

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Source

Identifiers

PMID: 24050204
DOI: 10.1021/np300894y

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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