Article
Physiological role of Acyl coenzyme A synthetase homologs in lipid metabolism in Neurospora crassa.
Eukaryotic cell - 1 Sept 2013
Roche Christine M, Blanch Harvey W, Clark Douglas S, Glass N Louise
Abstract excerpt
Acyl coenzyme A (CoA) synthetase (ACS) enzymes catalyze the activation of free fatty acids (FAs) to CoA esters by a two-step thioesterification reaction. Activated FAs participate in a variety of anabolic and catabolic lipid metabolic pathways, including de novo complex lipid biosynthesis, FA β-oxidation, and lipid membrane remodeling. Analysis of the genome sequence of the filamentous fungus Neurospora crassa...
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