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Article

Isolation of a Saccharomyces cerevisiae long chain fatty acyl:CoA synthetase gene (FAA1) and assessment of its role in protein N-myristoylation.

The Journal of cell biology - 1 May 1992

Duronio R J, Knoll L J, Gordon J I

Abstract excerpt

Regulation of myristoylCoA pools in Saccharomyces cerevisiae plays an important role in modulating the activity of myristoylCoA:protein N-myristoyltransferase (NMT), an essential enzyme with an ordered Bi Bi reaction that catalyzes the transfer of myristate from myristoylCoA to greater than or equal to 12 cellular proteins. At least two pathways are available for generating myristoylCoA: de novo synthesis by the...

Topics

Acyl Coenzyme A
Amino Acid Sequence
Base Sequence
Chromosome Mapping
Chromosomes, Fungal
Cloning, Molecular
Coenzyme A Ligases
Fatty Acid Synthases
Genetic Complementation Test
Isoenzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Myristic Acid

Myristic Acids

Phenotype

Protein Processing, Post-Translational

RNA, Messenger

Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1572893
DOI: 10.1083/jcb.117.3.515
PMCID: PMC2289438

Genes

FAS
NMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1572893-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Isolation of a Saccharomyces cerevisiae long chain fatty acyl:CoA synthetase gene (FAA1) and assessment of its role in protein N-myristoylation.PMID 1572893Read ↗

Suppressors of nmtl-181, a conditional lethal allele of the Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase gene, reveal proteins involved in regulating protein N-myristoylation.Semantic proximity Read ↗

A role for Saccharomyces cerevisiae fatty acid activation protein 4 in regulating protein N-myristoylation during entry into stationary phase.Semantic proximity Read ↗

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