Article
Chemotherapy response in East Asian non-small cell lung cancer patients harboring wild-type or activating mutation of epidermal growth factor receptors.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2010
Lin Chia-Chi, Hsu Hsin-Hsin, Sun Chia-Tung, Shih Jin-Yuan, Lin Zhong-Zhe, Yu Chong-Jen, Chen George G, Hsin Michael Kuan Yew, Lam Kwok Chi, Leung Linda, Yang Chih-Hsin, Mok Tony
Abstract excerpt
INTRODUCTION: Previous exploratory analysis of epidermal growth factor receptor (EGFR) mutational status in tumor samples from randomized clinical studies suggested that patients with activating mutation of the EGFR had better survival than those harboring wild-type EGFR. METHODS: We analyzed the EGFR sequence of tumor samples from advanced stage non-small cell lung cancer patients previously participated in...
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