Article
Polymorphism of UBC9 gene encoding the SUMO-E2-conjugating enzyme and breast cancer risk.
Pathology oncology research : POR - 1 Jan 2014
Wozniak Katarzyna, Krupa Renata, Synowiec Ewelina, Morawiec Zbigniew
Abstract excerpt
UBC9 protein (E2-conjugating enzyme) plays a key role in post-translation modification named sumoylation. Proteins, which are sumoylated take part in many cellular processes including cell growth, maintaining the genome integrity and stability and cancer development. The aim of this study was to investigate an association between three polymorphisms of the UBC9 gene: c.73G>A (rs11553473), c.430T>G (rs75020906)...
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