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Article

Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments.

Nature biotechnology - 1 Aug 2013

Wills Quin F, Livak Kenneth J, Tipping Alex J, Enver Tariq, Goldson Andrew J, Sexton Darren W, Holmes Chris

Abstract excerpt

Gene expression in multiple individual cells from a tissue or culture sample varies according to cell-cycle, genetic, epigenetic and stochastic differences between the cells. However, single-cell differences have been largely neglected in the analysis of the functional consequences of genetic var...

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PMID: 23873083
DOI: 10.1038/nbt.2642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23873083-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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