Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial gene polymorphisms that protect mice from colitis.

Gastroenterology - 1 Nov 2013

Bär Florian, Bochmann Wiebke, Widok Andrea, von Medem Kilian, Pagel Rene, Hirose Misa, Yu Xinhua, Kalies Kathrin, König Peter, Böhm Ruwen, Herdegen Thomas, Reinicke Anna T, Büning Jürgen, Lehnert Hendrik, Fellermann Klaus, Ibrahim Saleh, Sina Christian

Abstract excerpt

BACKGROUND & AIMS: Dysregulated energy homeostasis in the intestinal mucosa frequently is observed in patients with ulcerative colitis (UC). Intestinal tissues from these patients have reduced activity of the mitochondrial oxidative phosphorylation (OXPHOS) complex, so mitochondrial dysfunction could contribute to the pathogenesis of UC. However, little is known about the mechanisms by which OXPHOS activity could...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphate
Share to Colitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dextran Sulfate

Share to DNA, Mitochondrial

Share to Mice, Inbred AKR

Share to Mice, Inbred NOD

Share to Mice, Inbred NZB

Share to Reactive Oxygen Species

Source

Identifiers

PMID: 23872498
DOI: 10.1053/j.gastro.2013.07.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial gene polymorphisms that protect mice from colitis.PMID 23872498Read ↗

Mitochondrial dysfunction in inflammatory bowel diseaseSemantic proximity Read ↗

The Role of Mitochondria Dysfunction in Inflammatory Bowel Diseases and Colorectal CancerSemantic proximity Read ↗

Ulcerative Colitis Is Under Dual (Mitochondrial and Nuclear) Genetic Control.Semantic proximity Read ↗

Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitisSemantic proximity Read ↗

NEAT1 modulates neutrophil functions via glycolysis to restrain mucosal inflammation in ulcerative colitisSemantic proximity Read ↗

A Mitochondrial Polymorphism Alters Immune Cell Metabolism and Protects Mice from Skin Inflammation.Semantic proximity Read ↗

Assessment of the Changes in Mitochondrial Gene Polymorphism in Ulcerative Colitis and the Etiology of Ulcerative Colitis-associated Colorectal Cancer.Semantic proximity Read ↗

Role of Energy Metabolism and Mitochondrial Function in Inflammatory Bowel DiseaseSemantic proximity Read ↗

Mitochondrial dysfunction in Crohn’s diseaseSemantic proximity Read ↗

Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated ImmunopathologySemantic proximity Read ↗

Male-specific association between MT-ND4 11719 A/G polymorphism and ulcerative colitis: a mitochondria-wide genetic association study.Semantic proximity Read ↗

MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.