Article
C3435T polymorphism of MDR1 gene with warfarin resistance.
Clinica chimica acta; international journal of clinical chemistry - 21 Oct 2013
Kim Yeongsic, Smith Andrew, Wu Alan H B
Abstract excerpt
BACKGROUND: Some patients show warfarin resistance needing more than 70 mg of warfarin per week. In this study, we examined if C3435T polymorphism of MDR1 gene could be a factor of warfarin resistance. METHODS: We examined 196 blood specimens from the patients who took warfarin more than 42 mg/week for at least 1 year. The subjects consisted of 74 European Americans, 59 African Americans, 42 Hispanic Americans...
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