Article
The -174G>C IL-6 gene promoter polymorphism and diabetic microvascular complications.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Apr 2009
Rudofsky G, Schlotterer A, Reismann P, Engel J, Grafe I A, Tafel J, Morcos M, Humpert P M, Nawroth P, Bierhaus A, Hamann A
Abstract excerpt
This study examined a possible association of the G>C polymorphism at nucleotide -174 in the promoter region of the interleukin-6 (IL-6) gene (rs1800795) with the prevalence of diabetic complications in 235 patients with type 1 and 498 patients with type 2 diabetes. Genotyping was performed using polymerase chain reaction (PCR) and subsequent cleavage by Nla III restriction endonuclease. Analyzing all diabetic...
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