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Article

Alzheimer's disease risk genes and the age-at-onset phenotype.

Neurobiology of aging - 1 Nov 2013

Thambisetty Madhav, An Yang, Tanaka Toshiko

Abstract excerpt

Despite the recent identification of several novel risk genes for Alzheimer's disease (AD), little is known about their influence on the age at onset (AAO) of AD. The AAO is a phenotype with a heritable component distinct from disease risk and may be a useful trait to study in the context of developing interventions for delaying the onset of AD. We studied the influence of 10 recently identified AD risk genes and...

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Identifiers

PMID: 23870418
DOI: 10.1016/j.neurobiolaging.2013.05.028
PMCID: PMC4038407

Genes

APOE
PICALM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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