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Article

Role of TNFSF15 variants in oral cancer development and clinicopathologic characteristics.

Journal of cellular and molecular medicine - 1 Nov 2022

Lu Hsueh-Ju, Chuang Chun-Yi, Su Chun-Wen, Chen Mu-Kuan, Yang Wei-En, Yeh Chia-Ming, Tang Chih-Hsin, Lin Chiao-Wen, Yang Shun-Fa

Abstract excerpt

Tumour necrosis family superfamily (TNFSF) member 15 (TNFSF15), encoded by TNFSF15, regulates immune responses and inflammation. However, the roles of TNFSF15 single-nucleotide variants (SNVs; formerly SNPs) in oral cavity squamous cell carcinoma (OCSCC) remain unclear. This case-control study included 2523 participants (1324 patients with OCSCC [52.5%] and 1199 healthy controls [47.5%]). The effects of TNFSF15...

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PMID: 36226563
DOI: 10.1111/jcmm.17569
PMCID: PMC9639028

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