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Article

Multiplexed DNA detection with a composite molecular beacon based on guanine-quenching.

The Analyst - 21 Sept 2013

Xiang Dong-Shan, Zhai Kun, Wang Lian-Zhi

Abstract excerpt

We developed a multiplexed DNA detection method with a composite molecular beacon (MB) probe based on guanine-quenching by synchronous fluorescence analysis. It is demonstrated by two types of tumor-suppressor genes namely exon segments of p16 (T1) and p53 (T2) genes. The composite MB probe includes two loops and two stems, and two fluorophores of 6-carboxyfluorescein group (FAM) and...

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PMID: 23869386
DOI: 10.1039/c3an01060k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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