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Article

Genetic determinants of aromatase inhibitor-related arthralgia: the B-ABLE cohort study.

Breast cancer research and treatment - 1 Jul 2013

Garcia-Giralt Natalia, Rodríguez-Sanz María, Prieto-Alhambra Daniel, Servitja Sonia, Torres-Del Pliego Elisa, Balcells Susana, Albanell Joan, Grinberg Daniel, Diez-Perez Adolfo, Tusquets Ignasi, Nogués Xavier

Abstract excerpt

A major side effect of aromatase inhibitor (AI) therapy is AI-related arthralgia (AIA), which often leads to therapy discontinuation. We aimed to identify genetic variants associated with AIA and therapy discontinuation in the first year of AI treatment. Our prospective cohort study included 343 postmenopausal women with early breast cancer starting AI therapy. Single nucleotide polymorphisms (SNPs) in candidate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23868189
DOI: 10.1007/s10549-013-2638-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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