Article
Indications of clinical and genetic predictors for aromatase inhibitors related musculoskeletal adverse events in Chinese Han women with breast cancer.
PloS one - 1 Jan 2013
Wang Jingxuan, Lu Kangping, Song Ying, Xie Li, Zhao Shu, Wang Yunxuan, Sun Wenzhou, Liu Lei, Zhao Hong, Tang Dabei, Ma Wenjie, Pan Bo, Xuan Qijia, Liu Hang, Zhang Qingyuan
Abstract excerpt
BACKGROUND: Women with breast cancer treated with aromatase inhibitors (AIs) may experience musculoskeletal symptoms that lead to discontinuation of effective therapy. The purpose of the current study is to evaluate the clinical and genetic predictors for AIs-related musculoskeletal adverse events(MS-AEs). METHODOLOGY AND PRINCIPAL FINDINGS: We recruited 436 postmenopausal Chinese Han women receiving adjuvant AIs...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Antineoplastic Agents
- Aromatase Inhibitors
- Asian People
- Breast Neoplasms
- Bridged-Ring Compounds
- Case-Control Studies