Article
Pharmacogenetics and aromatase inhibitor induced side effects in breast cancer patients.
Pharmacogenomics - 1 Jun 2017
Sini Valentina, Botticelli Andrea, Lunardi Gianluigi, Gori Stefania, Marchetti Paolo
Abstract excerpt
This paper reviews genetic variations mainly related to the onset of adverse events during aromatase inhibitors in early breast cancer. Genetic variability could occur at different steps. The analysis included studies that involved breast cancer patients, treated with an aromatase inhibitor, genotyped for CYP19A1 and/or CYP17A1 and/or CYP27B1 and/or TCLA1, and/or RANK/RANKL/OPG and/or ESR1/ESR2, and assessed for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
