Article
Distinct patterns of DNA methylation in conventional adenomas involving the right and left colon.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2014
Koestler Devin C, Li Jing, Baron John A, Tsongalis Gregory J, Butterly Lynn F, Goodrich Martha, Lesseur Corina, Karagas Margaret R, Marsit Carmen J, Moore Jason H, Andrew Angeline S, Srivastava Amitabh
Abstract excerpt
Recent studies have shown two distinct non-CIMP methylation clusters in colorectal cancer, raising the possibility that DNA methylation, involving non-CIMP genes, may play a role in the conventional adenoma-carcinoma pathway. A total of 135 adenomas (65 left colon and 70 right colon) were profile...
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