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Right and left-sided colon cancers - specificity of molecular mechanisms in tumorigenesis and progression

15 Apr 2020

Abstract excerpt

BACKGROUND: Given the differences in embryonic origin, vascular and nervous supplies, microbiotic burden, and main physiological functions of left and right colons, tumor location is increasingly suggested to dictate tumor behavior affecting pathology, progression and prognosis. Right-sided colon cancers arise in the cecum, ascending colon, hepatic flexure and/or transverse colon, while left-sided colon cancers...

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PMID: 32293332
DOI: 10.1186/s12885-020-06784-7

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