Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Staphylococcal Ecb Protein and Host Complement Regulator Factor H Enhance Functions of Each Other in Bacterial Immune Evasion

18 Jul 2013

Abstract excerpt

Staphylococcus aureus is a major human pathogen causing more than a tenth of all septicemia cases and often superficial and deep infections in various tissues. One of the immune evasion strategies of S. aureus is to secrete proteins that bind to the central complement opsonin C3b. One of these, extracellular complement binding protein (Ecb), is known to interfere directly with functions of C3b. Because C3b is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacterial Infections and Vaccines
Share to Complement system in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23863906
DOI: 10.4049/jimmunol.1300638

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Staphylococcal Ecb Protein and Host Complement Regulator Factor H Enhance Functions of Each Other in Bacterial Immune EvasionPMID 23863906Read ↗

Microbes Bind Complement Inhibitor Factor H via a Common SiteSemantic proximity Read ↗

Staphylococcus aureus virulence is enhanced by secreted factors that block innate immune defenses.Semantic proximity Read ↗

Neisseria meningitidis recruits factor H using protein mimicry of host carbohydratesSemantic proximity Read ↗

Dual interaction of factor H with C3d and glycosaminoglycans in host–nonhost discrimination by complementSemantic proximity Read ↗

Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion.Semantic proximity Read ↗

Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.Semantic proximity Read ↗

Functional Significance of Factor H Binding to Neisseria meningitidisSemantic proximity Read ↗

The Protease SplB of Staphylococcus aureus Targets Host Complement Components and Inhibits Complement-Mediated Bacterial OpsonophagocytosisSemantic proximity Read ↗

Hijacking Complement Regulatory Proteins for Bacterial Immune EvasionSemantic proximity Read ↗

vhp Is a Fibrinogen-Binding Protein Related to vWbp in Staphylococcus aureusSemantic proximity Read ↗

The group B streptococcal beta and pneumococcal Hic proteins are structurally related immune evasion molecules that bind the complement inhibitor factor H in an analogous fashion.Semantic proximity Read ↗

Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.