Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1–11

27 Dec 2013

Abstract excerpt

Histone deacetylases (HDACs) have the ability to cleave the acetyl groups of ε-N-acetylated lysine residues in a variety of proteins. Given that human cells contain thousands of different acetylated lysine residues, HDACS may regulate a wide variety of processes including some implicated in conditions such as cancer and neurodegenerative disorders. Herein we report the synthesis and in vitro biochemical profiling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Click Chemistry and Applications
Share to Histone Deacetylase Inhibitors Research
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24375963
DOI: 10.1002/cmdc.201300433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1–11PMID 24375963Read ↗

Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding GroupsSemantic proximity Read ↗

Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding GroupsSemantic proximity Read ↗

Medicinal chemistry advances in targeting class I histone deacetylasesSemantic proximity Read ↗

Targeting Histone Deacetylases: Opportunities for Cancer Treatment and ChemopreventionSemantic proximity Read ↗

Structure-Based Inhibitor Discovery of Class I Histone Deacetylases (HDACs)Semantic proximity Read ↗

Recent advances in class IIa histone deacetylases researchSemantic proximity Read ↗

Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological ActionabilitySemantic proximity Read ↗

Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for ClearanceSemantic proximity Read ↗

Histone Deacetylase 11 is an ε- <i>N</i> -Myristoyllysine HydrolaseSemantic proximity Read ↗

Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer AgentsSemantic proximity Read ↗

A Therapeutic Perspective of HDAC8 in Different Diseases: An Overview of Selective InhibitorsSemantic proximity Read ↗

Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot-Marie-Tooth Type 2A Mouse Model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.