Article
Killer immunoglobulin-like receptor (KIR) centromeric-AA haplotype is associated with ethnicity and tuberculosis disease in a Canadian First Nations cohort.
PloS one - 1 Jan 2013
Braun Kali, Larcombe Linda, Orr Pamela, Nickerson Peter, Wolfe Joyce, Sharma Meenu
Abstract excerpt
Killer immunoglobulin-like receptors (KIR) on natural killer (NK) cells interact with other immune cells to monitor the immune system and combat infectious diseases, such as tuberculosis (TB). The balance of activating and inhibiting KIR interactions helps determine the NK cell response. In order to examine the enrichment or depletion of KIRs as well as to explore the association between TB status and...
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