Article
Susceptibility to pulmonary tuberculosis in Iranian individuals is not affected by compound KIR/HLA genotype.
Tissue antigens - 1 Feb 2012
Tajik N, Shah-hosseini A, Mohammadi A, Jafari M, Nasiri M, Radjabzadeh M F, Farnia P, Jalali A
Abstract excerpt
Natural killer (NK) cells have distinctive functional capacities that are likely to contribute both to innate and adaptive immunity to Mycobacterium tuberculosis. Killer cell immunoglobulin-like receptors (KIR) and their ligands, i.e. human leukocyte antigen (HLA) class I molecules contribute partly in regulation of NK cell activity. In this study, the impact of compound KIR/HLA genotype on susceptibility to...
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