Article
Studies on correlation between single-nucleotide polymorphisms of tumor necrosis factor gene and different stages of ankylosing spondylitis.
Cell biochemistry and biophysics - 1 Jan 2013
Ji Yinghua, Yang Xiaoyu, Yang Lin, Wu Dapeng, Hua Fangfang, Lu Tan, Jia Jinling, Ma Chao, Liang Qiudong
Abstract excerpt
To examine if there is any correlation between ankylosing spondylitis (AS) and TNF-α gene promoter single-nucleotide polymorphisms (SNP) and their associated haplotypes. Using restriction fragment length polymorphism-polymerase chain reaction method, the polymorphism of TNF-α-238, -308, -850, -857, -863 locus, and TNF-β +252 were analyzed in patients with progressive AS, stable AS and control. (1) Neither the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
