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Article

Low methylation rates of dopamine receptor D2 gene promoter sites in Japanese schizophrenia subjects.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Sept 2016

Yoshino Yuta, Kawabe Kentaro, Mori Takaaki, Mori Yoko, Yamazaki Kiyohiro, Numata Shusuke, Nakata Shunsuke, Yoshida Taku, Iga Jun-Ichi, Ohmori Tetsuro, Ueno Shu-Ichi

Abstract excerpt

OBJECTIVES: According to the dopamine hypothesis, several studies on the gene for the dopamine receptor D2 (DRD2) have been conducted. However, no trait biomarkers on DRD2 are available. We examined whether the methylation rates in the upstream region of DRD2 in leukocytes are different in schizophrenia (SCZ) subjects compared to control subjects. METHODS: We selected seven CpG sites in the upstream region of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27269479
DOI: 10.1080/15622975.2016.1197424

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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